Wet age-related macular degeneration (wet AMD) is a serious eye condition that primarily affects people over 60, causing rapid loss of central vision. The disease is driven by abnormal blood vessel growth beneath the retina, triggered by excessive levels of vascular endothelial growth factor (VEGF). These vessels leak fluid and blood, leading to swelling, scarring, and irreversible vision impairment if untreated. Innovations like Allergan Anti-VEGF therapies have dramatically improved management of this condition.

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Understanding Wet AMD

The macula, located in the center of the retina, is responsible for detailed vision. In wet AMD, VEGF stimulates new blood vessels to form abnormally, which can leak and damage this critical area. Symptoms often appear suddenly, including blurred vision, wavy lines, and dark spots in the center of vision. Early diagnosis is crucial because treatment is far more effective when started promptly.

How Allergan Anti-VEGF Therapy Works

Allergan’s anti-VEGF treatments block the VEGF protein, halting the growth of abnormal blood vessels. By reducing leakage and swelling, these therapies stabilize vision and can even improve it. Abicipar Pegol, an Allergan drug developed in collaboration with Molecular Partners, offers longer-lasting effects, potentially reducing the number of injections needed each year. This represents a meaningful advancement for patient convenience and adherence.

Current Treatment Landscape

In addition to Allergan therapies, other anti-VEGF medications such as ranibizumab (Lucentis), aflibercept (Eylea), and bevacizumab (Avastin) are commonly used. Treatments involve regular intravitreal injections, typically every 4–8 weeks. Follow-up exams allow ophthalmologists to monitor retinal health and adjust treatment as necessary, maximizing visual outcomes.

Living with Wet AMD

Early intervention with anti-VEGF therapy, including Allergan’s solutions, allows many patients to preserve functional vision. Lifestyle modifications—like quitting smoking, eating a diet rich in leafy greens and antioxidants, and using UV-protective eyewear—support long-term eye health. For those with vision impairment, low-vision aids and rehabilitation programs help maintain independence.