Wet age-related macular degeneration (wet AMD) is a rapidly progressing eye disease affecting central vision in adults over 60. It is caused by abnormal growth of blood vessels under the macula, driven by high levels of VEGF, which leads to leakage, swelling, and scarring. Thanks to innovations like Allergan Anti-VEGF therapy, effective management and vision preservation are now possible for millions of patients.

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How Wet AMD Affects Vision

The macula is crucial for sharp vision needed for reading, driving, and recognizing faces. When abnormal vessels form and leak, patients may notice distortion, blurred vision, or dark spots in the center of their sight. Early detection is key, as timely intervention can prevent permanent vision loss.

Mechanism of Allergan Anti-VEGF Drugs

Allergan Anti-VEGF treatments target VEGF to block abnormal vessel formation and leakage. Abicipar Pegol, developed in collaboration with Molecular Partners, offers extended treatment intervals, potentially reducing injection frequency while preserving efficacy. This innovation improves both patient compliance and overall treatment outcomes.

Complementary Treatments and Management

Alongside Allergan therapies, other anti-VEGF drugs such as ranibizumab, aflibercept, and bevacizumab are administered via intravitreal injections. Regular monitoring allows ophthalmologists to adjust therapy, ensuring optimal visual results. Emerging sustained-release devices may further reduce injection frequency in the future.

Supporting Vision and Quality of Life

Treatment is most effective when combined with healthy lifestyle measures, including smoking cessation, antioxidant-rich nutrition, and UV eye protection. For those experiencing vision loss, low-vision aids and rehabilitation programs help maintain independence and enhance daily living.

Conclusion

Allergan Anti-VEGF therapy has significantly advanced the treatment of wet AMD, offering hope for preserved vision and improved quality of life. Through early diagnosis, ongoing treatment, and lifestyle support, patients can manage the disease effectively and maintain functional eyesight.